Multiple myeloma is a disease characterized by the clonal proliferation of. Mieloma multiple natalia weber estrada summary multiple myeloma mm is a debilitating malignancy that is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance to plasma cell leukemia. Changing clinical presentation of multiple myeloma. Who classification of tumours of haematopoietic and lymphoid tissues, 4th edition 2002 7. It is defined by the presence of monoclonal plasma cells capable to produce a monoclonal paraprotein causing clinical abnormalities such as anemia, renal insufficiency, hypercalcemia, or bone lesions. Idiotypebased immunotherapy has been explored in myeloma patients with disappointing results.
Mieloma multiplo, mieloma multiplo diagnostico laboratorial, mgus, mieloma multiplo smoldering. Mieloma multiple hematologia y oncologia manual msd version. Mieloma multiple hematologia y oncologia manual msd. Mieloma multiple diagnostico, estudio y tratamiento autores dr. Jul 08, 2017 mieloma multiplemieloma multiple epidemiologia 1. Please use one of the following formats to cite this article in your essay, paper or report. Guillermo conte l 1,7, gaston figueroa m 1, vivianne lois v 2, maria elena cabrera c 3, alvaro leon r 4, hernan garcia l 5, hernan rojas r 6. Informacion sobre informacion sobre linfomas y mielomas. Feb 11, 2015 vivir con mieloma multiple entrevista a pepe monge, paciente con mieloma duration. Multiple myeloma is a malignant neoplasm, characterized by uncontrolled proliferation of the plasma cells.
It is caractherized by an uncontrolled proliferation of lymphoid b cells and plasmatic cells in the bone marrow. It is a disorder of great clinical relevance within malignant hematological disorders and remains incurable. Multiple myeloma is the second most common hematological malignancy. Feb 27, 2019 please use one of the following formats to cite this article in your essay, paper or report. The idiotype protein, secreted by myeloma plasma cells, is a tumorspecific but weak antigen. Mieloma multiplo hematologia e oncologia manuais msd. Clinical features and survival of chilean patients with multiple myeloma.
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